Web17 jun. 2016 · Major concern when using larger fraction size is cardiac toxicity. In contrary to common belief that hypofractionation has a harmful effect on the heart, it is noteworthy to remember that EQD2 of the hypofraction schedule is gentler to the heart than conventional fractionation. Web18 jun. 2024 · We tested experimental ultra-hypofractionation using 6·1 Gy per fraction to a total dose of 42·7 Gy delivered every other day in 2·5 weeks compared with standard conventional fractionation using 2 Gy per fraction to a total dose of 78 Gy in 8 weeks, and found that ultra-hypofractionation is non-inferior to standard fractionated radiotherapy …

Hypofractionated ablative radiotherapy for locally advanced …

WebAims: Hypofractionation of postoperative radiotherapy for breast cancer has been evaluated in a number of large randomised clinical trials, but concerns remain over the … tkinter vertical

Modern Hypofractionation Schedules for Tangential Whole …

Web6 dec. 2014 · Hypothesizing on an α/β-level of 1.5 Gy for prostate cancer and of 3 Gy for rectum, it can be concluded that prostate cancer cells are more responsive to a larger fraction size and that due to a lower α/β-level of prostate cancer cells in comparison with the surrounding late responding tissues there is even a therapeutic gain by using larger … Web28 jan. 2024 · For now, moderate hypofractionation with 40–42.5 Gy over 15–16 fractions remains the standard of care for the majority of patients with breast cancer who undergo whole-breast radiotherapy without regional nodal … Webhypothesis that prostate cancer has a low αβ ratio. 9,10 Hypofractionation, using fraction sizes >2 Gy per day, may therefore be radiobiologically advantageous. Conventional fractionation (doses-per-fraction in the range 1.8–2 Gy) The results of conventional fractionation have been comprehensively reviewed and reported. tkinter using an image as a button