Gefitinib smpc
WebMar 14, 2016 · Gefitinib is an orally active selective small-molecule inhibitor of the EGFR tyrosine kinase, which, upon binding (with 10 times higher affinity to sensitive mutations … WebSep 17, 2024 · The active substance in Iressa, gefitinib, is a protein-tyrosine-kinase inhibitor. This means that it blocks specific enzymes known as tyrosine kinases. These …
Gefitinib smpc
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WebThe metabolism of gefitinib is via the cytochrome P450 isoenzyme CYP3A4 (predominantly) and via CYP2D6. Active substances that may increase gefitinib plasma … WebMar 3, 2024 · 1. Stop imatinib until ANC ≥1.5 x 10 9 /l and platelets ≥75 x 10 9 /l. 2. Resume treatment with imatinib at 600 mg. 3. In the event of recurrence of ANC <1.0 x 10 9 /l and/or platelets <50 x 10 9 /l, repeat step 1 and resume imatinib at reduced dose of 400 mg. ANC=absolute neutrophil count.
WebThis is a summary of the European public assessment report (EPAR) for Giotrif. It explains how the European Medicines Agency assessed the medicine to recommend its authorisation in the European Union (EU) and its conditions of use. It is not intended to provide practical advice on how to use Giotrif. WebErlotinib is eliminated by hepatic metabolism and biliary excretion. Although erlotinib exposure was similar in patients with moderately impaired hepatic function (Child -Pugh score 7-9) compared with
WebFeb 10, 2024 · Gefitinib 250 mg film coated tablets smpc- taj pharmaceuticals Taj Pharma Vildagliptin Tablets Taj Pharma SmPC TajPharmaQC Vemurafenib 240 mg film coated tablets smpc- taj pharmaceuticals Taj Pharma Simvastatin Tablets USP … WebAug 19, 2024 · Vizimpro 45 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) Vizimpro 45 mg film-coated tablets Active Ingredient: dacomitinib monohydrate Company: Pfizer Limited See contact details ATC code: L01EB07 About Medicine Prescription only medicine Healthcare Professionals (SmPC) Patient Leaflet (PIL)
WebOverview Vizimpro is a cancer medicine used to treat adults with non small cell lung cancer (NSCLC) when the disease is advanced or has spread. Vizimpro is used on its own and only in patients with certain mutations (changes) in the gene for a protein called epidermal growth factor receptor (EGFR).
WebJan 6, 2024 · Corneal erosion, reversible and sometimes in association with aberrant eyelash growth. Haemorrhage, such as epistaxis and haematuria. Interstitial lung disease (1.3%), often severe (CTC grade 3-4). Cases with fatal outcomes have been reported. Diarrhoea, mainly mild or moderate (CTC grade 1 or 2). ectopic pregnancy no missed periodWebFeb 10, 2024 · Print SmPC information. Expand All. 1. Name of the medicinal product. Erlotinib 100 mg film-coated tablets. 2. Qualitative and quantitative composition. Each film-coated tablet contains 100 mg erlotinib (as … ectopic pregnancy on ultrasoundWebDec 15, 2024 · ZEPATIER 50 mg/100 mg film coated tablets - Summary of Product Characteristics (SmPC) - (emc) ZEPATIER 50 mg/100 mg film coated tablets Active Ingredient: elbasvir, grazoprevir Company: Merck Sharp & Dohme (UK) Limited See contact details ATC code: J05AP54 About Medicine Prescription only medicine ectopic pregnancy online quiz