Cspg4-creert2

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August undefined, 2024

WebProtocol 27167: Standard PCR Assay - Generic Cre/ERT2 alternate1 Version 1. 2 Notes This assay will NOT distinguish hemizygous from homozygous transgenic animals. The genotyping protocol (s) presented here have been optimized for reagents and conditions used by The Jackson Laboratory (JAX). WebCol1a1-CreERT2 Molecular description: The transgene consists of a tamoxifen-inducible cre recombinase driven by the 2.3-kb mouse Col1a1, collagen, type I, alpha 1, promoter. The transgene insert contains a fusion product involving cre recombinase and a mutant form of the mouse estrogen receptor ligand binding domain. The mutant mouse estrogen ...

Pericyte-like spreading by disseminated cancer cells activates

WebThis search provides access to all the entity’s information of record with the Secretary of State. For information on ordering certificates and/or copies of documents, refer to the … WebJan 1, 2016 · Homeowners aggrieved by their homeowners associations (HOAs) often quickly notice when the Board of Directors of the HOA fails to follow its own rules, or … peachtree city griffin ga

008538 - NG2-CreER[TM] Strain Details - The Jackson …

WebDownload scientific diagram ERβ-ligand treatment induced remyelination during EAE. (A) Representative EM images of ultraresolution axons and myelin in the spinal cords of WT EAE mice treated ... WebJul 6, 2024 · Cspg4 CreERT2 mice express the tamoxifen-inducible Cre-recombinase under the control of Cspg4 promoter. Cspg4 CreERT2 mice were used to label cardiac … WebUpon induction, the recombination occurs in the NG2 positive cells (OPCs and pericytes). The membrane-bound GFP (mGFP) is selectively expressed in myelinating OLs, as it is under the control of ... peachtree city golf cars

Frontiers Chondroitin Sulfate Proteoglycan 4 and Its Potential …

CSPG4 chondroitin sulfate proteoglycan 4 [ (human)]

WebBy using this site, you agree to our Terms and Conditions Got it! WebJun 25, 2024 · Protein kinase CK2 is a crucial regulator of endothelial cell proliferation, migration and sprouting during angiogenesis. However, it is still unknown whether this kinase additionally affects the angiogenic activity of other vessel-associated cells. In this study, we investigated the effect of CK2 inhibition on primary human pericytes. We found … lighthouse figurines wholesaleWebJun 14, 2024 · NG2 (nerve/glia antigen-2) is a type I transmembrane glycoprotein and also known as chondroitin sulfate proteoglycan 4. In the parenchyma of the central nervous … peachtree city golf cart sales

"WebAug 12, 2016 · In these experiments, Tg (Cspg4-dsRed.T1)1Akik reporter mice were used to identify the in vivo expression pattern of NG2. In Pdgfratm11 (EGFP)Sor knockin reporter mice, PDGFRα expression is... " - Cspg4-creert2

Cspg4-creert2

Tg (Col1a1-cre/ERT2)1Crm - Skeletal System

WebArticle Snippet: Cspg4 CreERT2 mice were used to label cardiac pericytes during embryonic development and is a validated model to label Cspg4 expressing cells and … WebJan 10, 2024 · CSPG4, also referred to as melanoma-associated chondroitin sulfate proteoglycan (MCSP), high-molecular-weight melanoma-associated antigen (HMW-MAA), or neuron-glial antigen 2 (NG2), was first associated with malignant melanoma and subsequently implicated in the pathology of other solid tumors of different origins, as well …

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WebAug 12, 2016 · Remarkably, mural cells expressing the markers platelet-derived growth factor receptor β (PDGFRβ), CD146 and NG2/Cspg4 have been proposed to function as mesenchymal stem cells in multiple organs and act as myofibroblast progenitors during injury-induced fibrosis16,17,18. WebApr 30, 2024 · For Cspg4-CreERT2/Mapt-GFP transgenic mice, tamoxifen (Sigma-Aldrich) was dissolved in corn oil (75 mg/kg) and administered s.c. 2 wk before ERβ-ligand …

WebJul 6, 2024 · Cspg4 CreERT2 mice were used to label cardiac pericytes during embryonic development and is a validated model to label Cspg4 expressing cells 35 and were … WebOct 21, 2024 · The NG2 (cspg4)-CreERT2 knock-in mouse line had been generated previously (Huang et al., 2014). CAG-EGFP reporter mice (CMV-β actin promoter and loxP flanked CAT gene18 upstream of the EGFP cassette; Nakamura et al., 2006 ) were obtained from Leda Dimou (Ulm).

WebUpon induction, the recombination occurs in the NG2 positive cells (OPCs and pericytes). The membrane-bound GFP (mGFP) is selectively expressed in myelinating OLs, as it is … WebNov 17, 2024 · Pdgfrb(BAC)-CreERT2 4, 33 or B6.Cg-Tg(Cspg4-cre/Esr1*) BAkik/J (NG2-CreER TM) BAC transgenic mice 35 were interbred with Rosa26-mTmG Cre reporter mice 34 or Rosa26-YFP Cre reporter mice …

WebJan 23, 2024 · The contribution of pericytes to the expansion of αSMA + vascular cells was assessed using the Cspg4-CreERTM;tdTomato flox (Cspg4-tdTomato) line, fibroblasts with the Pdgfra-CreERT2; tdTomato flox (Pdgfra-tdTomato) line, and ECs using Cdh5-CreERT2;tdTomato flox (Cdh5-tdTomato) mice (supplementary material, Figure

WebJul 13, 2024 · BMSC populations were genetically labeled with a range of tamoxifen-inducible Cre alleles, namely Pdgfrb-CreERT2 (Walker et al., 2024), ... Sp7-mcherry and Cspg4-DsRed reporter mice were used for MSC characterization. Pdgfra-GFP and Sp7-mcherry mice were crossed to generate double transgenic reporter mice. Hey1-GFP (Tg ... peachtree city golf clubWebJun 28, 2024 · CSPG4-directed immunotherapy may be approached in several ways, including: (1) antibody-based fusion proteins for the selective delivery of a pro-apoptotic factors such as tumor necrosis factor-related apoptosis-inducing ligand to agonistic death receptors 4 and 5 on the cell surface; and (2) CSPG4-specific immunotoxins which bind … peachtree city golf cartsWebTamoxifen诱导Cre-ERT2小鼠使用指南. Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似 … lighthouse figurines collectibles